Acetyl hexapeptide-1 | CAS 448944-47-6 | Anti-Wrinkle Peptide for Skin Rejuvenation

Description Contents hide 1 Product Description 2 Product Specifications 3 Mechanism of Action 3.1 1. Neuromuscular Signal Modulation 3.2 2. Collagen and Elastin Support 3.3 3. Anti-Wrinkle and Skin Smoothing 3.4 4. Barrier Function Enhancement 3.5 5. Synergistic Activity 4 Side Effects 5 Keywords 6 Shipping Guarantee 7 Trade Assurance 8 Payment Support 9 Disclaimer Product DescriptionAcetyl hexapeptide-1 is a synthetic peptide composed of six amino acids, designed to mimic the N-terminal end of SNAP-25, a protein involved in neurotransmitter release. By modulating neuromuscular signaling pathways, it reduces the intensity of muscle contractions responsible for dynamic facial wrinkles.Laboratory studies indicate that Acetyl hexapeptide-1 can inhibit exocytosis of neurotransmitters in keratinocytes and fibroblasts, indirectly relaxing underlying facial muscles. This mechanism has made it a prominent research peptide in cosmetic science, especially in studies focusing on the reduction of crow’s feet, forehead lines, and frown lines.In vitro research demonstrates that Acetyl hexapeptide-1 enhances dermal matrix integrity by increasing collagen and elastin deposition over prolonged treatment periods. It also contributes to skin barrier support by modulating keratinocyte proliferation and differentiation.Due to its small molecular size and lipophilic modifications, Acetyl hexapeptide-1 shows efficient skin penetration, allowing researchers to explore its use in topical serum, cream, and lotion formulations. Its stability and reproducibility in laboratory experiments make it a reliable tool for peptide-based cosmetic research.Furthermore, Acetyl hexapeptide-1 has been explored in combination with other anti-aging peptides, antioxidants, and hydrating agents to achieve synergistic effects in anti-wrinkle and skin rejuvenation studies. Its multifunctional profile enables scientists to investigate both neuromuscular and dermal pathways for improved cosmetic outcomes.Product SpecificationsItemDetailsProduct NameAcetyl hexapeptide-1CAS Number448944-47-6SynonymsMelitane, N-Acetyl-Hexapeptide-1Molecular FormulaC46H56N12O10Molecular Weight888.0 g/molPurity≥99%AppearanceWhite to off-white lyophilized powderSolubilitySoluble in water, PBS, and DMSOpH StabilityStable between pH 5–7Storage Temperature2–8 °CCategoryCosmetic peptideApplicationsAnti-wrinkle research, neuromuscular modulation studies, collagen synthesis research, skin rejuvenation studiesFormulationSuitable for topical serum, cream, or lotion research formulationsStabilityStable under recommended storage and light-protected conditionsShelf Life24 monthsSupplier TypeFactory peptide supplier / OEM cosmetic peptide manufacturerIntended UseFor laboratory research use onlyMechanism of ActionAcetyl hexapeptide-1 acts by modulating neuromuscular signaling and dermal regeneration pathways:1. Neuromuscular Signal ModulationThe peptide interacts with SNAP-25, a key protein in neurotransmitter release, to reduce muscle contraction intensity. This mechanism helps decrease the formation of dynamic facial wrinkles in laboratory models.2. Collagen and Elastin SupportAcetyl hexapeptide-1 promotes fibroblast activity, enhancing the synthesis of collagen types I and III and elastin fibers. This contributes to dermal structural integrity and improved skin elasticity.3. Anti-Wrinkle and Skin SmoothingBy reducing facial muscle micro-contractions and supporting ECM protein deposition, Acetyl hexapeptide-1 smooths fine lines and wrinkles, aiding in the study of visible skin rejuvenation.4. Barrier Function EnhancementThe peptide also promotes keratinocyte differentiation and epidermal barrier maintenance, which is essential for skin hydration and resilience against environmental stress.5. Synergistic ActivityResearch shows that Acetyl hexapeptide-1 can work in combination with other peptides, antioxidants, and moisturizing agents to produce additive or synergistic effects in anti-aging and wrinkle-reduction studies.Side EffectsCytotoxicity: Low in controlled research concentrations; safe for laboratory experiments.Irritation: Minimal, as observed in reconstructed human skin models.Phototoxicity: Not reported; safe for topical experimental models.Storage Considerations: Sensitive to heat, light, and extreme pH; store at 2–8 °C.Experimental Guidance: Recommended to perform concentration-dependent assays to assess peptide efficacy and biocompatibility.Acetyl hexapeptide-1 is strictly for research use and is not intended for ingestion, injection, or clinical treatment.KeywordsAcetyl hexapeptide-1, Melitane, anti-wrinkle peptide, skin rejuvenation, neuromuscular modulation, cosmetic peptide research, factory peptide supplier, peptide wholesale China, cosmetic raw material manufacturer, low-price peptide supplier, high-purity cosmetic peptides, China peptide manufacturer, OEM & bulk peptide production, high purity.Shipping GuaranteeAll shipments are handled using validated cold-chain logistics to preserve peptide integrity. Each package is sealed in moisture-proof containers with secondary protective wrapping and continuous temperature monitoring. Products are shipped via express international couriers with full tracking and insurance coverage.Trade AssuranceWe Acetyl hexapeptide-1 ensure product authenticity, verified ≥99% purity, and compliance with analytical standards (HPLC, MS, and NMR). Each batch is supplied with a Certificate of Analysis (CoA). Our trade assurance policy guarantees replacement or refund for any deviation from listed specifications.Payment SupportWe Acetyl hexapeptide-1 provide flexible and secure global payment options to support international research transactions. Accepted payment methods include PayPal, major credit cards (Visa, MasterCard, American Express), telegraphic transfer (T/T), and cryptocurrencies (USDT, Bitcoin, Ethereum). All transactions are protected by industry-standard encryption and verified payment gateways to ensure confidentiality and fund security.https://arizona-mall.com/wp-content/uploads/2025/11/Videos-acetyl-hexapeptide-1-cas-448944-47-6-.mp4DisclaimerAll Acetyl hexapeptide-1 products listed are intended for laboratory research use only and not for human or veterinary use. They are not drugs, medical devices, or diagnostics and should not be administered to humans or animals. Researchers must handle all materials in accordance with institutional biosafety and chemical safety guidelines. The information provided is for scientific reference only and does not imply therapeutic efficacy, safety, or regulatory approval.